Additional Research Studies at Reliant Medical Group

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Reliant Medical Group Southboro Medical - Now a part of Reliant Medical Group (800) 283-2556 (508) 481-5500

PLEASE NOTE: Listed below are studies that are being conducted by the Reliant Medical Group research department. This list is for informational purposes only.

Promoting Breast Cancer Screening in Non-Adherent Women #1191

This study is designed to identify the optimum strategy for increasing mammography utilization in Fallon Clinic patients who have Fallon Community Health Plan Insurance. Investigators will also measure the cost effectiveness of two interventions in comparison to standard of care.

Investigators and support staff: Robert Yood, MD (Reliant Medical Group Rheumatology) & Daniel Roswig, MD (Reliant Medical Group Radiology), Susan Sama ScD, Devi Sundaresan, MS, Meagan Fair and Belinda James (Reliant Medial Group Research).

Funding: National Cancer Institute in collaboration with UMass Medical School.

International Costs and Utilities Related to Osteoporotic Fractures (ICUROS) #1221

Its purpose is to investigate the consequences of osteoporosis-related fractures in terms of costs and health-related quality of life.

Investigators and support staff: Robert Yood, MD & John Reed, MD, (Reliant Medical Group Clinic Rheumatology), Peggy Preusse, RN and Mary Charpentier (Reliant Medical Group Research).

Funding: Osteoporosis Medical Center.

Breath Analysis using Quantum Cascade Lasers: Phase II #1105

The purpose of the study is to test a new breath analyzer that may be faster, cheaper, easier to use, and more accurate than older methods. Investigators will analyze participants’ breath for trace gases known to be markers of asthma and other lung diseases. They will conduct 4 clinical studies, two involving pediatric asthma, one involving adult asthma, and one involving COPD (adults). Currently analyzing data.

Investigators and support staff: Richard Rosiello, MD (Reliant Medical Group Pulmonary), Robert Kossack, MD (Reliant Medical Group Pediatrics), Susan Sama, ScD, Devi Sundaresan, MS, Diane Gannon, RN, Janet Guilbert, RN (Reliant Medical Group Research).

Funding: National Institutes of Health (NIH) in collaboration with Aerodyne Research and UMass Lowell.

Worcester VTE Community Surveillance Project #856

The overall aim of this multi-hospital community-wide observational study is to establish a population-based surveillance system for monitoring the current incidence, short and long-term case fatality rates, treatment approaches, and medical care utilization patterns associated with VTE. Patients with DVT episodes will be interviewed periodically over a two-year period. Currently analyzing data.

Investigators and support staff: Luigi Pacifico, MD (Reliant Medical Group Cardiology) and Anne McDonald, RN, Kathleen Allain, LPN, Devi Sundaresan, MS, Doris Hoyer, MS, Kathy Barrett, RN (Reliant Medical Group Research).

Funding: National, Heart, Lung & Blood Institute (NHLBI) in collaboration with UMass Medical School.

Monitoring Community Trends in Heart Failure #804

The overall aim of this multi-hospital community-wide observational study is to establish population-based surveillance for monitoring changes over time in the incidence, in-hospital and long-term case-fatality rates, treatment approaches, and medical care utilization patterns associated with heart failure. Currently analyzing data.

Investigators and support staff: Stephen Pezzella, MD (Reliant Medical Group Cardiology) and Diane Gannon, RN, Peggy Preusse, RN, Devi Sundaresan, MS, Kathy Barrett, RN (Reliant Medical Group Research).

Funding: National, Heart, Lung & Blood Institute (NHLBI) in collaboration with UMass Medical School.

Health Care Delivery Process Improvement and Electronic Health Record Implementation #1070

This study follows changes in workflows and satisfaction of patients, physicians and staff through the stages of implementing our Epic Electronic Health Record (EHR). It also compares our implementation to similar EHR implementations at UMass, in Canada, and in Israel. Reliant Medical Group will use the information gleaned from this study to optimize our workflows.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics), John Trudel, MD (Reliant Medical Group Family Practice), Devi Sundaresan, MS, Peggy Preusse, RN. (Reliant Medical Group Research).

Funding: National Science Foundation (NSF) in collaboration with Worcester Polytechnic Institute (WPI).

Improving Posthospital Medication Management of Older Adults through Health IT #1132

The overall aim is to determine the effects of a post-discharge medication reconciliation intervention including the use of information technology, on serious medical errors and on the use of the emergency room and hospital readmissions.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics), Donna Curboy (Information Technology), Devi Sundaresan, MS, Peggy Preusse, RN. (Reliant Medical Group Research). Currently analyzing data.

Funding: The Agency for Healthcare Research and Quality (AHRQ) in collaboration with Meyers Primary Care Institute.

Using HIT to Improve Transitions of Complex Elderly Patients from SNF to Home (Rampage II) #1179

To test use of an EMR-based medication reconciliation system for a particularly high-risk population and care transition – complex elderly patients transitioning from sub acute care in a skilled nursing facility to the ambulatory setting.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics), Donna Curboy (Information Technology), Devi Sundaresan, MS, Peggy Preusse, RN (Reliant Medical Group Research).

Funding: The Agency for Healthcare Research and Quality (AHRQ) in collaboration with Meyers Primary Care Institute.

Risk Informed Intervention to Improve Ambulatory Drug Monitoring and Safety. #1178

The overall goal is to improve patient safety by implementing an intervention directed at improving the rate of ordering and completion of therapeutic laboratory monitoring of high-risk medications in the ambulatory setting.

Investigators and support staff: Lawrence Garber, MD (Fallon Clinic Informatics), Carlo Vivenzio & James Underwood (Information Technology), Devi Sundaresan, MS, Peggy Preusse, RN. (Reliant Medical Group Research).

Funding: The Agency for Healthcare Research and Quality (AHRQ) in collaboration with Meyers Primary Care Institute.

Proximity to Traffic, Air Toxic Exposures and the Development of Asthma in Children #1006

(Richard Rosiello, M.D., Pulmonary)

The objective is to examine how traffic related air toxics are associated with changes in respiratory symptoms and exhaled nitric oxide, a marker of airway inflammation in children. We will study sibling pairs where the older sibling is asthmatic and the younger pre-school sibling is at high risk of developing asthma. Staff conducted home visits to collect health and exposure data. As part of the study a webpage with fact sheets and resources on the study, childhood asthma, air pollution and asthma, healthy homes for asthmatics and other topics can be found at: http://www.uml.edu/college/she/WE/Proximity_to_Air_Toxic_Project.html.
Currently analyzing data.

Investigators and support staff: Richard Rosiello, MD (Reliant Medical Group Pulmonary) Susan Sama, ScD, Janet Guilbert, RN and Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: The Mickey Leland National Urban Air Toxics Research Center in collaboration with the UMass Lowell.

CONtrolling Disease Using Inexpensive IT-Hypertension in Diabetes CONDUIT-HID #1272

This study seeks to test an approach to improve management of chronic health conditions amenable to patient self-monitoring that takes advantage of commercial, off-the-shelf technology (automated BP cuffs with USB interfaces and Microsoft HealthVault, a secure, free PHR) and can be implemented in health care settings ranging from those with a full EHR and web portal to those with no HIT beyond internet access. Subjects will use either home computers or a PC at their practice site. Investigators have chosen hypertension in diabetes as the test condition.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics), Michael Kelleher, MD (Quality and Patient Safety), Devi Sundaresan, MS & Peggy Preusse, RN (Reliant Medical Group Research) and Madeline Wronski, RN (Reliant Medical Group Clinical Effectiveness).

Funding: The Agency for Healthcare Quality and Research (AHRQ) in collaboration with UMass Medical Center.

Home and Community Exposures in COPD Exacerbation: A Pilot Case Cross-Over #1287

To identify triggering environmental exposures in the days immediately preceding an exacerbation by comparing these exposures to those in randomly chosen weeks when participants are not experiencing exacerbations. Currently analyzing data.

Investigators and support staff: Richard Rosiello, MD (Reliant Medical Group Pulmonary) Susan Sama, ScD & Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: The National Institutes of Health (NIH) in collaboration with the UMass Lowell.

Health Outcomes Associated with Opioid-Related Side Effects #1253

Its purpose is to better understand the frequency of side effects associated with opioid use and their prescription and OTC drug treatment as well as the costs associated with opioid-related side effects. Currently analyzing data.

Investigators and support staff: John Reed, MD (Reliant Medical Group Rheumatology), Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: Analysis Group.

Study of Patients with Severe Peripheral Arterial Disease (PAD) #1300

The goal of the study is to look at the current medication management, disease progression and key clinical outcomes, as well as associated resource utilization and direct medical costs, among patients with severe peripheral arterial disease (PAD). Currently analyzing data.

Investigators and support staff: Leon Josephs, MD (Reliant Medical Group Surgery), Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: Boston HealthEconomics (BHEI).

Clinical and economic burden of side effects associated with hormone therapy among menopausal women #1343

The purpose of the study is to assess the discontinuation of hormone replacement therapy among menopausal women, and the contribution of side effects to discontinuation and their associated economic burden. Study completed; analyzing data.

Investigators and support staff: Craig Best, MD (Reliant Medical Group Ob/Gyn) and Judith Gilmore, Devi Sundaresan, MS & Kathleen Barrett, RN (Reliant Medical Group Research)

Funding: Boston HealthEconomics (BHEI).

Improving Massachusetts Post- Acute Care Transfers; IMPACT # 1326

The purpose of the project is to connect post-acute care providers to hospitals and physician offices via the HIE Challenge Grant funding in a low-cost and sustainable way that accommodates the varying levels of technology available within each organization and aligns with the state’s Health IT and HIE action plans. This project will complete development and testing of a) a paper and b) an electronic version of the state’s Universal Transfer Form (UTF) based on the Clinical Document Architecture Standard (CDA)/Continuity of Care Document (CCD), to consistently and efficiently communicate all of the clinical information necessary for continuity of care. A goal of this project is to also develop a tool that translates clinical information into consumer-friendly language that is meaningful and easy to understand for patients and families for use in a personal health record (PHR) or printing on paper because patients are essential to the communication and execution of treatment.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics), Devi Sundaresan, MS, Susan Sama, ScD, Peggy Preusse RN and Judith Gilmore (Reliant Medical Group Research.

Funding: The Federal Government under an HIE Challenge Grant out of the HHS/ONC. The grant revenues will flow to the Massachusetts Technology Collaborative, the official state HIE Cooperative Agreement grant recipient.

Development of a COPD Specific Risk Assessment Using Medical and Pharmacy Claims #1396

This is a retrospective, longitudinal cohort study using data from electronic medical records (EMR) and insurance claims to evaluate the risk for exacerbations in patients with COPD. Study completed; analyzing results.

Investigators and support staff: Richard Rosiello MD (Reliant Medical Group Pulmonary), Devi Sundaresan MS, Judy Gilmore & Mary Charpentier (Reliant Medical Group Research).

Funding: Analysis Group, Inc.

Burden of Illness and Treatment Patterns in Non-Transfusion-Dependent Thalassemia (NTDT) Patients: a Medical Record Review Study #1390

Overall study objective is to understand the distribution of thalassemia subtypes in a community based health center and evaluate burden of illness associated with thalassemia (i.e., complications, transfusion burden, treatment patterns, resource use, and costs). Study completed; analyzing results.

Investigators and support staff: Saleem Khanani MD (Reliant Medical Group Oncology), Devi Sundaresan MS, Diane Gannon RN & Diane Kirk RN (Reliant Medical Group Research).

Funding: Analysis Group, Inc.

Descriptive Analysis of the prevalence and treatment-related consequences of thrombocytopenia in HCV patients in the US #1354

Its purpose is to look at the prevalence of thrombocytopenia in patients with HCV, ability to treat the underlying HCV infection and changes in antiviral treatment patterns and clinical outcomes. Study completed; analyzing results.

Investigators and support staff: Gregory Williams, MD (Reliant Medical Group Infectious Disease), Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: Outcomes Research.

Evaluating the Factors Associated with cardiovascular events in rheumatoid arthritis #1372

The overall objective is to develop a better understanding of the factors associated with cardiovascular events in rheumatoid and psoriatic arthritis. Study completed; analyzing results.

Investigators and support staff: Julie Levengood, MD (Reliant Medical Group Rheumatology) and Devi Sundaresan, MS (Reliant Medical Group Research).

Funding: IMS Consulting Group.

Impact of Self-Monitoring of Blood Glucose (SMBG) Use on Newly Diagnosed, Insulin-Naïve Adult Type 2 Diabetes Patients’ Outcomes #1355

The objective of this study is to compare the outcomes of newly diagnosed and insulin-naïve patients with type 2 diabetes using SMBG versus those not using SMBG. The study endpoints include glycemic control (measured as HbA1c), blood pressure control, lipid control, weight and body mass index (BMI) change from baseline, kidney damage, and healthcare costs. Study completed; analyzing results.

Investigators and support staff: Lawrence Garber, MD (Reliant Medical Group Informatics) and Devi Sundaresan, MS (Reliant Medical Group Research)

Funding: Analysis Group, Inc.

Analysis of an electronic medical record Database to better understand utilization and outcomes in benign prostatic hyperplasia (bph) and hypogonadism #1359

The purpose of the study is to evaluate the clinical, economic & patient burden of BPH and hypogonadism in the U.S. Study completed; analyzing data.

Investigators and support staff: Brett Carswell, MD (Reliant Medical Group Urology) and Devi Sundaresan, MS, Judith Gilmore (Reliant Medical Group Research).

Funding: IMS Consulting Group

Genetic Determinants of COPD and COPD Exacerbations #1143

The genetic determinants of COPD exacerbations are completely unknown. Identification of genetic determinants of COPD and COPD exacerbations will require the application of state of the art genetic epidemiological approaches to well-characterized COPD patients and control subjects without COPD. Genetic variants will be compared in COPD subjects with frequent exacerbations vs. COPD subjects with infrequent exacerbations to test candidate genes for association with susceptibility for COPD exacerbations. Genetic variants will be compared in COPD cases and control subjects to identify genetic determinants of COPD. Study has been extended.

Investigators and support staff: Richard Rosiello, M.D. (Reliant Medical Group Pulmonary) Diane Kirk, RN and Anne McDonald, R.N. and Kathy Allain, L.P.N. (Research)

Funding: National Health, Lung and Blood Institute (NHLBI) in collaboration with Brigham & Women’s’ Hospital.

Mortality and Hospitalization Rates in Patients with Severe Chronic Obstructive Pulmonary Disease Receiving Long-Term Oxygen Therapy, LTOT #1421

The objective of this study is to measure mortality and hospitalization rates in patients with severe chronic obstructive pulmonary disease (COPD) who are receiving long term oxygen therapy (LTOT).

Investigators and support staff: Richard Rosiello, M.D. (Reliant Medical Group Pulmonary) and Devi Sundaresan MS (Reliant Medical Group Research.

Funding: Boston HealthEconomics (BHEI).