Medical Mythbuster: Is “Ozempic Butt” an Actual Medical Problem?

Chances are, you’ve heard of Ozempic and similar medications such as Wegovy that have been all over the news and social media recently.

Ozempic (semaglutide) is an injectable drug that belongs to a class of medications called GLP-1 receptor agonists. It is typically used to control blood glucose (sugar) levels in patients with type 2 diabetes. Ozempic isn’t FDA approved for weight loss, but because of how it works in the body many patients lose weight as a side effect. (Some other GLP-1 agonists have recently been approved for weight loss.)

Now some users of these drugs are complaining of sagging skin due to weight loss, sometimes referred to as “Ozempic Butt.” Whether it occurs from diet, exercise or medication, any significant weight loss can cause loose, saggy skin. Losing weight quickly, such as by using a medication containing semaglutide, can make this problem worse. This is because the skin takes time to reshape itself and adjust to weight loss.

Muscle breakdown from a lack of nutrients can further worsen the saggy skin appearance from fat loss. So, if you are taking Ozempic or another GLP-1 agonist, you should make sure you are eating enough protein and otherwise maintaining a proper diet to keep the muscles in your body healthy.

If you are taking any weight-loss drug, it’s very important to keep your healthcare provider informed of any side effects you might be experiencing including diarrhea, nausea, constipation, bloating, hair loss, as well as saggy skin. You may need to make adjustments to your dosage or diet to correct problems.

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